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Author (up) Padeganeh, A.; De Rop, V.; Maddox, P.S.
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  Title Nucleosomal composition at the centromere: a numbers game Type Journal Article
  Year 2013 Publication Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology Abbreviated Journal Chromosome Res  
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  Abstract The Centromere is a unique chromosomal locus where the kinetochore is formed to mediate faithful chromosome partitioning, thus maintaining ploidy during cell division. Centromere identity is inherited via an epigenetic mechanism involving a histone H3 variant, called centromere protein A (CENP-A) which replaces H3 in centromeric chromatin. In spite of extensive efforts in field of centromere biology during the past decade, controversy persists over the structural nature of the CENP-A-containing epigenetic mark, both at nucleosomal and chromatin levels. Here, we review recent findings and hypotheses regarding the structure of CENP-A-containing complexes.  
  Address Institute for Research in Immunology and Cancer (IRIC), University of Montreal, Montreal, H3T1J4, QC, Canada  
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  Language English Summary Language Original Title  
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  Series Volume Series Issue Edition  
  ISSN 0967-3849 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:23328870 Approved no  
  Call Number @ @ Serial 37341  
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